Fig. 9

The degree of oxidative stress was determined by immunohistochemical staining for 4-HNE. Mice were fed the ND (a, c and e) or HFD (b, d and f) for 25 weeks and treated with 0 (a, b), 100 (c, d), or 300 (e, f) mg of SNPs kg−1 body weight twice per week. The scale bars represent 100 µm (a–f). The percentage of positive 4-HNE staining/area was analyzed using Image-Pro (g). The data are presented as the means ± standard errors of the means (n = 6)